Frequently Asked Questions
What VRAYLAR Is
VRAYLAR® (cariprazine) is a once-a-day pill, taken with or without food, for the treatment of schizophrenia in adults.
Medical researchers believe that schizophrenia may be caused by an imbalance of certain chemicals in the brain called neurotransmitters. VRAYLAR is thought to affect the activity of neurotransmitters. However, the exact way VRAYLAR works is unknown.
Tell your healthcare provider about any medical conditions and if you:
- have or have had heart problems or a stroke
- have or have had low or high blood pressure
- have or have had diabetes or high blood sugar in you or your family
- have or have had high levels of total cholesterol, LDL-cholesterol, or triglycerides; or low levels of HDL-cholesterol
- have or have had seizures (convulsions)
- have or have had kidney or liver problems
- have or have had low white blood cell count
- are pregnant or plan to become pregnant. VRAYLAR may harm your unborn baby. Talk to your healthcare provider about the risk to your unborn baby if you take VRAYLAR during pregnancy. If you become pregnant or think you are pregnant during treatment, talk to your healthcare provider about registering with the National Pregnancy Registry for Atypical Antipsychotics at 1-866-961-2388 or
- are breastfeeding or plan to breastfeed. It is not known if VRAYLAR passes into breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with VRAYLAR
Tell your healthcare provider about all medicines that you take, including prescriptions, over-the-counter medicines, vitamins, and supplements. VRAYLAR may affect the way other medicines work, and other medicines may affect how VRAYLAR works. Do not start or stop any medicines while taking VRAYLAR without talking to your healthcare provider.
VRAYLAR is an oral capsule that is taken once daily with or without food. It is important that you take your prescribed dose of VRAYLAR as directed, even if you start to feel better.
In addition to treatment, it’s important to remember to surround yourself with a trusted support system. That can include friends, family, or patient support groups who can help you stay consistent with your treatment.
Medications like VRAYLAR tend to work gradually, so it may take some time for you to notice your symptoms improve. That’s why it’s important to take VRAYLAR exactly as prescribed.
Do not take VRAYLAR if you are allergic to any of its ingredients. Get emergency medical help if you are having an allergic reaction (eg, rash, itching, hives, swelling of the tongue, lip, face or throat).
Possible Side Effects
The most common side effects include difficulty moving or slow movements, tremors, uncontrolled body movements, restlessness and feeling like you need to move around, sleepiness, nausea, vomiting, and indigestion.
Have you ever wondered, “Could what I’m feeling be a side effect of my medication?” Call your healthcare provider right away and explain in detail what you are experiencing so they can tell you what to do. Always call your healthcare provider if you have questions about your medication or your dosing.
Weight gain has been reported with VRAYLAR. In 6-week clinical studies, patients with schizophrenia who took VRAYLAR experienced an average weight gain of 2.2 pounds, compared to those on placebo who gained about 0.7 pounds. You and your doctor should monitor your weight regularly.
An increase in blood sugar has been reported with VRAYLAR. If you have diabetes or risk factors for diabetes (eg, being overweight or family history of diabetes), your blood sugar should be tested before you start VRAYLAR and regularly during treatment. Complications of diabetes can be serious and even life-threatening. Tell your healthcare provider if you have symptoms such as feeling very thirsty, or very hungry, or sick to your stomach, urinating more than usual, or feeling weak, tired, confused, or your breath smells fruity.
An increase in cholesterol has been reported with VRAYLAR. Your healthcare provider should check your cholesterol and triglyceride levels before and during treatment.
In 6-week clinical studies, 7% of patients with schizophrenia who took VRAYLAR felt sleepy or drowsy. In comparison, 6% of patients taking placebo felt sleepy or drowsy.
Feeling restless or like you need to move around has been reported with VRAYLAR. In the 6-week clinical studies, 11% of patients with schizophrenia who took VRAYLAR felt restless or like they needed to move around (akathisia) as compared to 4% of patients taking placebo.
Schizophrenia is a chronic condition. That means it’s lifelong and there is no cure. But for many people, the symptoms may be helped with treatment.
Schizophrenia is seen more often in people with a sibling or parent (a first-degree relative) who have the condition. Research is being done to try to determine the genes that may be linked to schizophrenia.