What Is
VRAYLAR?

VRAYLAR is a prescription medicine approved as an add-on therapy for adults with major depressive disorder (MDD) who are currently taking an antidepressant but still have unresolved depression symptoms.

How could VRAYLAR help me?

Adding VRAYLAR to your current antidepressant can help you build on the progress you’ve made so you don’t have to start over.

In 6- and 8-week studies, adults, on average, experienced improvement in their overall depression symptoms after adding VRAYLAR to their antidepressant vs an antidepressant alone.

Examples of common primary antidepressants that were taken with VRAYLAR in clinical studies†‡

SSRI
antidepressant


Prozac® (fluoxetine)

Paxil® (paroxetine)

Zoloft® (sertraline)

SNRI
antidepressant


Cymbalta® (duloxetine)

Effexor® (venlafaxine)

NDRI
antidepressant


Wellbutrin® (bupropion hydrochloride)

SSRI = selective serotonin reuptake inhibitor; SNRI = serotonin and norepinephrine reuptake inhibitor; NDRI = norepinephrine and dopamine reuptake inhibitor

These are not all the antidepressants studied with VRAYLAR. Ask your healthcare provider if adding VRAYLAR is right for you.

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How does VRAYLAR work?

VRAYLAR is a once-daily capsule. While the exact way VRAYLAR works is unknown, healthcare providers and scientists
believe that VRAYLAR helps manage chemicals in the brain, such as serotonin and dopamine, that control your mood.


How do I take VRAYLAR?

Treatments like VRAYLAR start working gradually. Every patient is different. So, it’s important to stick with your treatment plan and talk to your healthcare provider about how VRAYLAR is working for you.

Things to keep in mind when taking VRAYLAR

One Pill. Take Once a Day

It’s important that you take your prescribed dose of VRAYLAR as directed, even if you start to feel better.

Take by Mouth

Do not stop taking VRAYLAR or change how much you take without checking with your healthcare provider first.

With or Without Food

Take VRAYLAR once a day, with or without food.


What are the most common side effects of VRAYLAR?

In clinical trials, the most common side effects were:

  • Difficulty moving or slow movements
  • Tremors
  • Uncontrolled body movements
  • Restlessness and feeling like you need to move around
  • Sleepiness
  • Nausea
  • Vomiting
  • Indigestion
  • Constipation
  • Feeling tired
  • Trouble sleeping
  • Increased appetite
  • Dizziness
  • Difficulty moving or slow movements
  • Tremors
  • Uncontrolled body movements
  • Restlessness and feeling like you need to move around
  • Sleepiness
  • Nausea
  • Vomiting
  • Indigestion
  • Constipation
  • Feeling tired
  • Trouble sleeping
  • Increased appetite
  • Dizziness

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of VRAYLAR.

Want more information? Find answers to common questions about VRAYLAR.

Depending on insurance coverage, eligible patients may pay as little as $5 for each of up to twelve (12) prescription fills. In such instances, eligible patients who have not previously registered for a VRAYLAR® (cariprazine) savings card may pay as little as $0 for their first two (2) 30-day fills. Eligible patients whose insurer does not cover VRAYLAR® (cariprazine) or where coverage restrictions have not been satisfied may pay as little as $75 per 30-day supply for each of up to twelve (12) prescription fills. Check with your pharmacist for your copay discounts. Maximum savings limit applies; patient out-of-pocket expenses may vary. Offer not valid for patients enrolled in Medicare, Medicaid, or other federal or state health care programs. Please see https://www.allergansavingscard.com/vraylar for Program Terms, Conditions, and Eligibility Criteria.

 Most new eligible patients may pay as little as $0 for their first two 30-day fills and as little as $5 for 30- or 90-day refills*
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