What is Depression?
Major depressive disorder (MDD), commonly referred to as depression, is one of the most common mental disorders in the United States. It’s characterized by a persistently depressed mood and loss of interest in the thing you enjoy.
Healthcare providers use various tools to evaluate a targeted list of symptoms to help determine if a patient has depression. Patients must experience five or more symptoms during the same 2-week period, with one of the symptoms being either depressed mood or loss of interest or pleasure.
Depression is most often treated with medicine or therapy, or a combination of both.
What is VRAYLAR?
VRAYLAR is a prescription medicine used along with antidepressant medicines to treat major depressive disorder (MDD) in adults.
If you have been taking an antidepressant and still have unresolved depressive symptoms, adding VRAYLAR may help.
VRAYLAR is a once-daily capsule that works with your antidepressant. VRAYLAR also works differently from your antidepressant. While the exact way VRAYLAR works is unknown, it is believed by scientists and doctors that VRAYLAR helps manage chemicals in the brain, such as serotonin and dopamine, that may control your mood.
The most common side effects include difficulty moving or slow movements, tremors, uncontrolled body movements, restlessness and feeling like you need to move around, sleepiness, nausea, vomiting, indigestion, constipation, feeling tired, trouble sleeping, increased appetite, and dizziness. These are not all the possible side effects of VRAYLAR.
Adjunctive treatment is taken in combination with an existing antidepressant medicine to help treat symptoms of depression.
Take VRAYLAR once daily, with or without food.
In 6- and 8-week studies, adults, on average, experienced improvement in their overall depression symptoms after adding VRAYLAR to their antidepressant vs an antidepressant alone.
Do not take VRAYLAR if you are allergic to any of its ingredients. Get emergency medical help if you are having an allergic reaction (eg, rash, itching, hives, swelling of the tongue, lip, face, or throat).
Tell your healthcare provider about any medical conditions and if you:
- have or have had heart problems or a stroke
- have or have had low or high blood pressure
- have or have had diabetes or high blood sugar in you or your family
- have or have had high levels of total cholesterol, LDL-cholesterol, or triglycerides; or low levels of HDL-cholesterol
- have or have had seizures (convulsions)
- have or have had kidney or liver problems
- have or have had low white blood cell count
- are pregnant or plan to become pregnant. VRAYLAR may harm your unborn baby. Taking VRAYLAR during your third trimester of pregnancy may cause your baby to have abnormal muscle movements or withdrawal symptoms after birth. Talk to your healthcare provider about the risk to your unborn baby if you take VRAYLAR during pregnancy. If you become pregnant or think you are pregnant during treatment, talk to your healthcare provider about registering with the National Pregnancy Registry for Atypical Antipsychotics at 1-866-961-2388 or http://www.womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/.
- are breastfeeding or plan to breastfeed. It is not known if VRAYLAR passes into breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with VRAYLAR.
Tell your healthcare provider about all medicines that you take, including prescriptions, over-the-counter medicines, vitamins, and supplements. VRAYLAR may affect the way other medicines work, and other medicines may affect how VRAYLAR works. Do not start or stop any medicines while taking VRAYLAR without talking to your healthcare provider.